William A Carroll Selected Research

dicyandiamido (cyanoguanidine)

5/2009	Discovery and biological evaluation of novel cyanoguanidine P2X(7) antagonists with analgesic activity in a rat model of neuropathic pain.
11/2007	Structure-activity studies of novel cyanoguanidine ATP-sensitive potassium channel openers for the treatment of overactive bladder.
1/2004	Design and synthesis of novel cyanoguanidine ATP-sensitive potassium channel openers for the treatment of overactive bladder.

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William A Carroll Research Topics

Disease

6	Overactive Urinary Bladder (Overactive Bladder) 11/2007 - 10/2002
4	Neuralgia (Stump Neuralgia) 01/2011 - 02/2008
3	Pain (Aches) 01/2011 - 02/2008
1	Postoperative Pain 04/2012
1	Hyperalgesia 01/2011
1	Inflammation (Inflammations) 01/2009
1	Peritonitis 05/2008
1	Chronic Pain 02/2008
1	Lower Urinary Tract Symptoms 09/2004
1	Urinary Bladder Neck Obstruction (Bladder Neck Obstruction) 10/2002

Drug/Important Bio-Agent (IBA)

4	Adenosine Triphosphate (ATP)IBA 09/2004 - 10/2002
3	Analgesics (Analgesic Drugs)IBA 01/2011 - 02/2008
3	dicyandiamido (cyanoguanidine)IBA 05/2009 - 01/2004
2	Biological ProductsIBA 05/2009 - 02/2008
2	KATP ChannelsIBA 11/2007 - 01/2004
2	9- (3- bromo- 4- fluorophenyl)- 2,3,5,6,7,9- hexahydrothieno(3,2- b)quinolin- 8(4H)- one 1,1-dioxideIBA 10/2002 - 10/2002
1	Messenger RNA (mRNA)IBA 01/2011
1	AM 1241IBA 01/2011
1	salicylhydroxamic acid (SHAM)IBA 01/2011
1	A-836339IBA 01/2011
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2011
1	CannabinoidsIBA 01/2011
1	Purinergic P2X7 ReceptorsIBA 01/2009
1	Mexiletine (Mexitil)FDA LinkGeneric 06/2008
1	furanIBA 06/2008
1	Lamotrigine (Lamictal)FDA LinkGeneric 06/2008
1	PiperazineIBA 06/2008
1	Sodium Channel BlockersIBA 06/2008
1	ZymosanIBA 05/2008
1	Antisense OligonucleotidesIBA 02/2008
1	Voltage-Gated Sodium ChannelsIBA 02/2008
1	Sodium Channels (Sodium Channel)IBA 02/2008
1	Tetrodotoxin (Tetradotoxin)IBA 02/2008
1	A-151892IBA 09/2004
1	PotassiumIBA 10/2002
1	1,4-dihydropyridine (dihydropyridine)IBA 10/2002

Therapy/Procedure

2	Analgesia 04/2012 - 02/2008
1	Ligation 01/2011